Sizzle and Nuzzle are an anthropomorphic orange female cat and brown male lop-eared dog, respectively. They are anthropomorphic animals, but they act as normal ones when they know they're in the presence of the Puzzle Place Kids. Of course, at one point, they see some human-like qualities in them sometimes. Also, in one of the wraparounds for the "Tuned In" video, they do partially act human at the hot dog stand when after ordering a hot dog, they pay with their toy replica of the Empire State Building. Sizzle and Nuzzle are usually involved in subplots. They act as sister and brother, respectively.