|“||You think water moves fast? You should see ice. It moves like it has a mind. Like it knows it killed the world once and got a taste for murder. After the avalanche, it took us a week to climb out. Now, I don't know exactly when we turned on each other, but I know that seven of us survived the slide... and only five made it out. Now we took an oath, that I'm breaking now. We said we'd say it was the snow that killed the other two, but it wasn't. Nature is lethal but it doesn't hold a candle to man.||„|
|~ Russell Franklin's monologue.|
At Aquatica, a remote former submarine refueling facility converted into a laboratory, a team of scientists is searching for a cure for Alzheimer's disease. Unknown to the other scientists, Dr. Susan McAlester violates a code of ethics and genetically engineers three Mako sharks to increase their brain capacity so their brain tissue can be harvested as a cure for Alzheimer's, but this causes the side effects to make the sharks smarter, faster, and more dangerous.
After one of the sharks escapes and attacks a boat full of teenagers, Aquatica's financial backers send corporate executive Russell Franklin to investigate the facility. To prove that the research is working, the team manages to remove brain tissue from the largest shark. While examining it, Dr. Jim Whitlock, one of the researchers, is attacked by the shark and his arm is bitten off. Brenda Kerns, the tower's operator, calls a helicopter to evacuate Jim but a strong hurricane causes the helicopter to lose control and crashes into the tower, killing Brenda and the pilots. One of the sharks uses Jim's body as a battering ram to smash an underwater window, flooding the research facility and freeing the other sharks. Susan then confesses to the others that she genetically altered the sharks.
Susan, Russell, Carter Blake, Janice Higgins and Tom Scoggins make their way to the top of the center. While delivering a dramatic speech emphasizing the need for group unity, Russell is dragged into the moon pool by the largest shark and devoured. He had sacrificed himself to save them.