Lance begins as a cadet at the Galaxy Garrison, a school for space exploration. He, Hunk, and Pidge are in the Garrison in the same year and assigned to the same cadet team. When Shiro, a Garrison pilot long thought dead in space, returns to Earth, they join with him and Keith to discover the Blue Lion.
When the Blue Lion brings them to Arus they meet Allura and Coran who tell them to look for the remaining Lions of Voltron so they can form the mighty robot and defeat the evil Galra empire. While he is initially the Blue Paladin, he becomes the Red Paladin once a need to change Lions arises.
Lance is a very flirtatious character known for his infatuation with any beautiful feminine human or alien he sees. Apart from his one-sided rivalry with Keith and his inflated ego, Lance is a great help, supporting his love interest, Allura, and goofing around with Pidge and Hunk.
- Lance was originally only known to be in his late teens. Jeremy Shada described Lance as being as young as 16. His age was published as being 17 in The Paladin's Handbook, which was not reviewed by executive series staff.
- Lance is Cuban. He grew up in or near Varadero.
- The Paladin's Handbook official guidebook gives garlic knots as Lance's favorite food.
- "The hunter becomes the hunted" is a quote in some of Lance's favorite movies.
- Lance has a very large family consisting of up to 12 family members
- It was revealed on the 100th episode of the Lets Voltron Podcast (released June 14, 2017) that Lance's birthday is July 28th.
- Lance's Weapons design has resemblance of the MA5D Assault rifle used by John-117 AKA the Master Chief from Halo. While his red paladin sniper has a unique design as it has the resemblance of the M41A Pulse Rifle used by Ellen Ripley From Aliens.